Trinh Thi Bich Tram

Whole blood transcriptional responses associated with bacterial burden in pulmonary tuberculosis

This study identifies a 1,093-gene module associated with Mtb burden in PTB, driven by neutrophils and monocytes, and highlights CNIH4 as a key predictor of bacterial burden.

Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis

This study uses scRNA-seq to analyze CSF and blood from TBM patients, identifying inflammatory cell subtypes and altered metabolic pathways in CSF.

Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

This study identifies gene modules, hubs, and pathways associated with TBM mortality using whole blood RNA sequencing and develops a 4-gene biomarker for predicting death from TBM.