Author

Truc-Mai Le

Brotman Baty Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Chengxiang QiuiD· 2 shared Cole TrapnelliD· 2 shared Diana R. O’DayiD· 2 shared Ian C. WelshiD· 2 shared Jay ShendureiD· 2 shared Megan L. TayloriD· 2 shared Riza M. DazaiD· 2 shared Stephen A. MurrayiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Chengxiang QiuORCID

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2 papers

Recent·Most cited

Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes

Chengxiang Qiu, Riza M. Daza, Ian C. Welsh, Rupali P Patwardhan, Beth K. Martin, Tony W. Li, Shizhao Yang, Camiel C. A. Mannens, Seppe De Winter, Niklas Kempynck, Megan L. Taylor, Olivia Fulton, Truc-Mai Le, Diana R. O’Day, Jean‐Benoît Lalanne, , Jay Shendure

The paper develops STEAM, an evolution-augmented deep learning model, to predict mammalian enhancer landscapes across species using comparative genomics and single-cell data.

bioRxiv · May 27, 2026 · PreprintGenomics

A single-cell transcriptional timelapse of mouse embryonic development, from gastrula to pup

Chengxiang Qiu, Beth Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay R Srivatsan, Xinxian Deng, Christine M. Distèche, , Jay Shendure

12.4 million single-nucleus transcriptomes from 83 staged mouse embryos (E8 to P0) yield 190 cell types, a zygote-to-pup cell-type tree, and rapid postnatal transcriptional shifts.

Nature · Feb 14, 2024Peer-reviewedDevelopmental Biology✦ In-depth digest