Mendelian randomization suggests a causal link between glycemic traits and thoracic aortic structures and diseases
Tselmen Daria, Kruthika Raman Iyer, Hasan Alkhairo, Pik Fang Kho, Suzuki Ken, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J. Taylor, Xianyong Yin, Ravi Mandla, Alicia Huerta‐Chagoya, W Rayner, Michael G. Levin, Scott M. Damrauer, Philip S. Tsao, , Catherine Tcheandjieu
This study uses Mendelian randomization to show that higher glycemic traits are inversely associated with thoracic aortic diameters and reduced risk of aneurysm and dissection.
JACC Basic to Translational Science · Oct 31, 2025Peer-reviewedGenetic & Genomic Medicine