Kruthika Raman Iyer

This study shows SIRPA inhibits integrin-dependent virus endocytosis by blocking a signaling pathway involving SHP2, SFKs, FAK, and alpha-integrin, offering therapeutic targets for RNA viruses.

The paper investigates why the 9p21.3 CAD risk locus fails to replicate in African ancestry cohorts, finding ancestry-specific LD and haplotype diversity explain the lack of association.

This study uses Mendelian randomization to show that higher glycemic traits are inversely associated with thoracic aortic diameters and reduced risk of aneurysm and dissection.

This study identifies 59 sentinel variants and two novel genes associated with telomere length using whole genome sequences from 109,122 trans-ethnic individuals.