Author

Tyler D. Robinson

Rotman Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

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Organism:human· 4 Assay:imaging· 4 Approach:statistical model· 4 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

J. Jean CheniD· 4 shared Paul T. H. Chang· 3 shared Yutong L. Sun· 3 shared Claudine Joëlle GauthieriD· 1 shared Fanghan E. Zhang· 1 shared Jordan A. ChadiD· 1 shared Koen Van LeemputiD· 1 shared Stefano CerriiD· 1 shared

Activity by Year

2023-2025 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 15 mutual co-author links

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4 shared papersNeuroscience

J. Jean ChenORCID

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4 papers

Recent·Most cited

Association between white-matter lesion volume and heart-rate variability: A comparison of T1w, T1w+T2w and T1w+FLAIR-based segmentations using FreeSurfer SAMSEG

Tyler D. Robinson, Stefano Cerri, Fanghan E. Zhang, Koen Van Leemput, J. Jean Chen

This paper examines the association between white-matter lesion volume and heart-rate variability using different MRI segmentation methods in a healthy adult cohort.

bioRxiv · Nov 18, 2025 · PreprintNeuroscience

Variations in perfusion detectable in advance of microstructure in white matter aging

Tyler D. Robinson, Yutong L. Sun, Paul T. H. Chang, Claudine Joëlle Gauthier, J. Jean Chen

This study examines the relationship between perfusion and white matter microstructure in aging, finding that arterial transit time declines before microstructural changes and varies by tract and sex.

GeroScience · Jul 22, 2025Peer-reviewedNeuroscience

Testing retrogenesis and physiological explanations for tract-wise white matter aging: links to developmental order, fibre calibre, and vascularization

Tyler D. Robinson, Jordan A. Chad, Yutong L. Sun, Paul T. H. Chang, J. Jean Chen

The paper investigates whether white matter aging follows developmental order (retrogenesis) or physiological factors like fibre size and perfusion, finding mixed support for both theories.

GeroScience · Jul 14, 2025Peer-reviewedNeuroscience

In search of a unifying theory of white matter aging: improving the understanding of tract-wise degeneration using multi-parametric signatures of morphometry and microstructure

Tyler D. Robinson, Yutong L. Sun, Paul T. H. Chang, J. Jean Chen

This study examines age-related changes in white matter tracts using morphometry and microstructural metrics to identify sex-specific degeneration patterns and propose a unified model of WM aging.

bioRxiv · Mar 14, 2023 · PreprintNeuroscience