Claudine Joëlle Gauthier

Physics and Morphology Constrained Quantitative Susceptibility Based Segmentation of Cerebral Veins

Dipole-field physics and Frangi vesselness losses lift QSM vein segmentation to centreline Dice 0.70 (U-Net 0.57); derived venous OEF tracks calibrated fMRI better than vessel filtering.

Regional distribution of white matter hyperintensity burden in coronary artery disease and links with coronary revascularization procedure

This study examines regional white matter hyperintensity (WMH) burden in coronary artery disease (CAD) and finds that CAD is associated with higher WMH volumes, with CABG linked to greater superficial WMH burden than PCI.

Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults

This study finds that higher cardiorespiratory fitness in older adults is linked to increased cerebral blood flow and decreased oxygen extraction fraction.

Coronary artery disease is linked with demyelination and iron deposition in white matter watershed areas

This study finds that coronary artery disease is associated with demyelination and increased iron deposition in white matter watershed regions, which correlate with cognitive decline.

Longitudinal functional connectivity during rest and task is differentially related to Alzheimer's pathology and episodic memory in older adults

The paper examines how changes in functional connectivity during rest and task relate to Alzheimer's pathology and episodic memory in older adults.

Reduced cerebrovascular reactivity in youth with complex congenital heart defects

This study finds persistent cerebrovascular reactivity deficits in youth with complex congenital heart defects compared to controls, with associations with cognitive performance.

Preservation of cerebral vascular and metabolic health with greater cardiorespiratory fitness in coronary artery disease

This study examines the relationship between cardiorespiratory fitness and cerebral vascular and metabolic health in CAD patients and healthy individuals, finding fitness improves vascular function and partially preserves metabolic function in CAD.

Multivariate white matter microstructure alterations in older adults with coronary artery disease

This study identifies white matter microstructural alterations in older adults with coronary artery disease using a multivariate approach and links them to cognitive performance.

Assessing Quantitative MRI Techniques using Multimodal Comparisons

The paper analyzes quantitative MRI metrics in healthy adults to understand their relationships and potential for uncovering cortical gradients.

Variations in perfusion detectable in advance of microstructure in white matter aging

This study examines the relationship between perfusion and white matter microstructure in aging, finding that arterial transit time declines before microstructural changes and varies by tract and sex.

Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility

This study examines how physical activity intensity and dose affect cerebrovascular reactivity and pulsatility differently in men and women, finding sex-specific patterns influenced by menopause.

Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease

The paper examines sex-specific and APOE4-related associations between cardiometabolic risk factors and white matter microstructure in individuals with a family history of Alzheimer's disease.

Cerebral blood perfusion across biological systems and the human lifespan

This study maps cerebral blood perfusion across the human lifespan and links it to brain structure, function, and disease vulnerability using ASL data from 1,305 individuals.

The Impact of Coronary Artery Disease on Brain Vascular and Metabolic Health: Links to Cognitive Function

This study investigates how coronary artery disease (CAD) affects cerebral vascular and metabolic health and links these changes to cognitive function, finding that reduced vascular reactivity and increased oxygen extraction fraction are associated with cognitive impairments.

Joint and Distinct Cognitive-Motor Associations with Multivariate White Matter Microstructure and Connectivity

The paper examines the relationship between white matter microstructure and cognitive-motor behavior using multivariate analysis, revealing distinct and overlapping associations across brain regions.

MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics

The paper introduces MVComp, a tool for computing Mahalanobis distance in brain MRI data to assess deviations from reference groups and provide insights into white matter microstructure.

Motor Sequences - Separating The Sequence From The Motor. A longitudinal rsfMRI Study

This study examines resting state functional connectivity changes after sequence-specific motor learning, finding sequence-specific decreases in the right supplementary motor area during overall learning.

Sex moderates the relationship between aortic stiffness, cognition and cerebrovascular reactivity in healthy older adults

This study examines how sex and hematocrit influence the relationship between aortic stiffness, cerebrovascular reactivity, and cognitive function in older adults.

White matter microstructural changes in short-term learning of a continuous visuomotor sequence

This study investigates white matter microstructural changes during short-term motor sequence learning using MRI scans and finds significant changes in early learning phases and functional connectivity.

High resolution atlasing of the venous brain vasculature from 7T quantitative susceptibility

This paper presents a high-resolution atlas of the human venous brain vasculature using 7T MRI data to characterize vessel location, diameter, and curvature.

Enhanced fitness relates to reduced cerebrovascular reactivity and perfusion in a sample of very healthy older adults

The paper examines the relationship between fitness, cerebral blood flow, and cerebrovascular reactivity in older adults, finding that higher fitness is associated with reduced cerebrovascular reactivity and altered hemodynamic responses.