Cancer BiologybioRxiv
A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations
I. M. Saldana-Guerrero, L. F. Montano-Gutierrez, K. Boswell…·F. Halbritter
The paper uses human embryonic stem cells to show that chromosomal gains in neuroblastoma impair neural crest development and enhance MYCN-driven tumourigenesis.