Author

C. Souilhol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

P. Evans· 3 shared V. Ridger· 3 shared H. Roddie· 2 shared J. Serbanovic-Canic· 2 shared L. Canham· 2 shared M. Ariaans· 2 shared M. FRAGIADAKI· 2 shared S. Francis· 2 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

P. Evans

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Author profile →

5 papers

Recent·Most cited

Assessment of ferroptosis inducers and Nrf2 inhibitors as radiosensitisers in 2D and 3D breast cancer cell cultures

A. A. Alzufairi, C. Souilhol, N. Jordan-Mahy, N. A. Cross

This study evaluates ferroptosis inducers and Nrf2 inhibitors as radiosensitizers in 2D and 3D breast cancer models, finding no significant enhancement of radiosensitivity.

bioRxiv · Dec 8, 2023 · PreprintCancer Biology

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

I. M. Saldana-Guerrero, L. F. Montano-Gutierrez, K. Boswell, C. Hafemeister, E. Poon, L. E. Shaw, D. Stavish, R. A. Lea, S. Wernig-Zorc, E. Bozsaky, I. S. Fetahu, P. Zoescher, U. Pötschger, M. Bernkopf, A. Wenninger-Weinzierl, , F. Halbritter

The paper uses human embryonic stem cells to show that chromosomal gains in neuroblastoma impair neural crest development and enhance MYCN-driven tumourigenesis.

bioRxiv · Nov 21, 2022Cancer Biology

JAG1-NOTCH4 MECHANOSENSING DRIVES ATHEROSCLEROSIS

C. Souilhol, X. Li, L. Canham, H. Roddie, D. Pirri, B. Tardajos Ayllon, E. Chambers, M. Dunning, M. Ariaans, J. Li, Y. Fang, M. FRAGIADAKI, V. Ridger, J. Serbanovic-Canic, S. De Val, , P. Evans

This study shows JAG1-NOTCH4 signaling promotes atherosclerosis by repressing endothelial repair in response to low oscillatory shear stress.

bioRxiv · May 15, 2020Pathology

β1 integrin is a sensor of blood flow direction

I. Xanthis, C. Souilhol, J. Serbanovic-Canic, H. Roddie, A. Kalli, M. Fragiadaki, R. Wong, D. Shah, J. Askari, L. Canham, N. Akhtar, S. Feng, V. Ridger, J. Waltho, E. Pinteaux, , P. Evans

This study identifies β1 integrin as a sensor for blood flow direction in endothelial cells, showing it is activated by unidirectional but not bidirectional shear stress.

bioRxiv · Jan 3, 2019Cell Biology

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium.

I. Gomez, B. Ward, C. Souilhol, C. Recarti, M. Ariaans, J. Johnston, A. Burnett, M. Mahmoud, L. A. Luong, L. West, M. Long, S. Parry, R. Woods, C. Hulston, B. Benedikter, , V. Ridger

The paper shows neutrophil microvesicles deliver miR-155 to atheroprone endothelium, promoting vascular inflammation and atherosclerosis in mice.

bioRxiv · May 24, 2018Cell Biology