U. Pozzoli

Simplexviruses successfully adapt to their host by fine-tuning immune responses

This study identifies positive selection in herpes simplex virus glycoproteins that influence immune escape mechanisms and HLA-G expression, explaining their adaptation to hominins.

Antigenic variation of SARS-CoV-2 in response to immune pressure

The paper analyzes SARS-CoV-2 genome diversity to show that B cell epitopes are more variable than non-epitope regions, while T cell epitopes show reduced variability, suggesting immune evasion strategies.