Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis
L. M. Muckenfuss, A. C. Migenda Herranz, F. M. Boneberg, M. Clerici, M. Jinek
This study reports two crystal structures of human Fip1 interacting with CPSF30 and CstF77, showing its role in mRNA 3' end processing by scaffolding and regulating PAP recruitment.
bioRxiv · May 31, 2022Biochemistry