Asymmetric oligomerization state and sequence patterning can tune multiphase condensate miscibility
U. Rana, K. Xu, A. Narayanan, M. T. Walls, A. Z. Panagiotopoulos, J. L. Avalos, C. P. Brangwynne
This study shows that increasing the oligomerization state of intrinsically disordered proteins enhances immiscibility and multiphase formation in biomolecular condensates.
bioRxiv · Mar 11, 2023Biophysics