Utsuki Yano

Improved Biosynthesis of Ethylene Glycol from Xylose in Engineered E. coli Utilizing Two-Stage Dynamic Control

This study improves ethylene glycol production from xylose in E. coli using two-stage dynamic control, achieving 140 g/L in 70 hours with 92% theoretical yield.

Decoupling Central Metabolism from Catabolite Repression Enables Robust Cellulosic Sugar Co-consumption in E. coli

This paper introduces a Gluconate-Bypass in E. coli to decouple central metabolism from catabolite repression, enabling robust co-consumption of multiple lignocellulosic sugars.

Engineering Orthogonal Carbon Dissimilation: A Gluconate Bypass Platform for Robust Stationary-Phase Biomanufacturing

This paper introduces a gluconate-bypass platform to enhance stationary-phase biomanufacturing in E. coli by decoupling glucose uptake from pyruvate inhibition and co-generating NADPH, achieving high product titers.