Author

V. A. Sardao

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Carvalho· 1 shared B. Silva· 1 shared F. B. Pereira· 1 shared H.-N. Kim· 1 shared M. Almeida· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

A. M. Carvalho

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1 paper

Recent·Most cited

The effect of estradiol during the early stages of osteoclast differentiation is associated with the accumulation of phosphorylated p53 in mitochondria and the inhibition of mitochondrial metabolism.

A. M. Carvalho, B. Silva, F. B. Pereira, H.-N. Kim, M. Almeida, V. A. Sardao

This study investigates how estradiol affects mitochondrial metabolism and apoptosis in osteoclast progenitors during early differentiation, revealing p53 accumulation in mitochondria as a key mechanism.

bioRxiv · Mar 30, 2023 · PreprintCell Biology