Phase separation by ssDNA binding protein controlled via protein-protein and protein-DNA interactions
G. M. Harami, Z. J. Kovacs, R. Pancsa, J. Palinkas, V. Barath, K. Tarnok, A. Malnasi-Csizmadia, M. Kovacs
This study shows that E. coli SSB forms liquid-liquid phase-separated condensates through interactions with ssDNA and other proteins, enabling rapid mobilization for DNA repair.
bioRxiv · Nov 20, 2019Biochemistry