Sirt1 overexpression attenuates high-fat diet induced aortic stiffening
V. Gogulamudi, D. R. Machin, G. D. Henson, A. J. Donato, L. A. Lesniewski
This study shows that Sirt1 overexpression reduces aortic stiffening and protects against vascular morphology changes in mice fed a high-fat diet.
bioRxiv · Oct 28, 2020 · PreprintPhysiology