Senolytic therapy combining Dasatinib and Quercetin restores the chondrogenic phenotype of human osteoarthritic chondrocytes by promoting the release of pro-anabolic mediators
S. Maurer, V. Kirsch, L. Ruths, R. E. Brenner, J. Riegger
Senolytic therapy with Dasatinib and Quercetin improves chondrocyte function in osteoarthritis by reducing senescence-associated secretory phenotype factors and increasing anabolic gene expression.
bioRxiv · Apr 4, 2024Cell Biology