Author

R. E. Brenner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:statistical model· 1

Frequent Co-Authors

J. Riegger· 2 shared S. Maurer· 2 shared A. Liebaug· 1 shared D. Rothenbacher· 1 shared J. Riegger-Koch· 1 shared L. Ruths· 1 shared S. S. Marques· 1 shared V. Kirsch· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

J. Riegger

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Author profile →

3 papers

Recent·Most cited

p53-induced GDF-15 expression promotes a pro-regenerative response in human chondrocytes upon cartilage injury

S. S. Marques, A. Liebaug, S. Maurer, D. Rothenbacher, R. E. Brenner, J. Riegger-Koch

This study identifies GDF-15 as a stress-responsive cytokine upregulated in PTOA, which promotes a pro-regenerative response in chondrocytes after cartilage injury.

bioRxiv · Apr 10, 2024 · PreprintCell Biology

Senolytic therapy combining Dasatinib and Quercetin restores the chondrogenic phenotype of human osteoarthritic chondrocytes by promoting the release of pro-anabolic mediators

S. Maurer, V. Kirsch, L. Ruths, R. E. Brenner, J. Riegger

Senolytic therapy with Dasatinib and Quercetin improves chondrocyte function in osteoarthritis by reducing senescence-associated secretory phenotype factors and increasing anabolic gene expression.

bioRxiv · Apr 4, 2024Cell Biology

Increase of cell surface vimentin (CSV) is associated with vimentin network disruption and subsequent stress-induced premature senescence (SIPS) in human chondrocytes

J. Riegger, R. E. Brenner

This study shows that increased cell surface vimentin (CSV) in chondrocytes is linked to vimentin network disruption and stress-induced premature senescence, contributing to osteoarthritis progression.

bioRxiv · May 8, 2023Cell Biology