Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations
T. Bengtsen, V. L. Holm, L. R. Kjolbye, S. R. Midtgaard, N. T. Johansen, G. Tesei, S. Bottaro, B. Schiott, L. Arleth, K. Lindorff-Larsen
This study integrates NMR, SAXS, SANS, and molecular dynamics simulations to characterize the structure and dynamics of two nanodiscs, revealing conformational heterogeneity and lipid ordering differences.
bioRxiv · Jun 23, 2020Biophysics