Author

N. T. Johansen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:structural biology· 5 Research Focus:protein structure prediction· 4 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

L. Arleth· 5 shared A. H. Larsen· 2 shared A. Martel· 2 shared K. Lindorff-Larsen· 2 shared M. C. Pedersen· 2 shared S. R. Midtgaard· 2 shared T. Bengtsen· 2 shared A. Bertarello· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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5 shared papersBiophysics

L. Arleth

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Ex vivo structures from spinach leaves

J. Wang, N. T. Johansen, L. F. Gamon, Z. Zhao, Z. Guo, Y. Wang, A. T. Fuglsang, P. Gourdon, K. Wang

The paper reports the structures of ten protein complexes from spinach leaves using a new ex vivo method that enables cryoEM-based high-resolution structure determination without genome manipulation or high-affinity binders.

bioRxiv · Oct 13, 2023 · PreprintBiochemistry

Refining structural models of membrane proteins withdisordered domains in phospholipid nanodiscs

M. C. Pedersen, N. T. Johansen, J. Roche, M. Jaarvaa, S. Tornroth-Horsefield, L. Arleth

This study refines structural models of membrane proteins with disordered domains using small-angle x-ray scattering in nanodiscs and introduces new computational methods and software.

bioRxiv · Oct 28, 2022 · PreprintBiophysics

Mg2+-dependent conformational equilibria in CorA: an integrated view on transport regulation

N. T. Johansen, M. Bonaccorsi, T. Bengtsen, A. H. Larsen, F. G. Tidemand, M. C. Pedersen, P. Huda, J. Berndtsson, T. Darwish, N. R. Yepuri, A. Martel, T. Pomorski, A. Bertarello, M. S. Sansom, M. Rapp, , L. Arleth

This study investigates the conformational dynamics of CorA, revealing Mg2+-dependent conformational equilibria and dynamic behavior through SANS, MD simulations, and NMR.

bioRxiv · Aug 20, 2021Biophysics

Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering

M. Lycksell, U. Rovsnik, C. Bergh, N. T. Johansen, A. Martel, L. Porcar, L. Arleth, R. J. Howard, E. Lindahl

This study uses small-angle neutron scattering to examine conformational changes in the bacterial ion channel GLIC under resting and activating conditions, finding no evidence for divergent mechanisms.

bioRxiv · Apr 10, 2021Biophysics

Lipid-bound ApoE3 self-assemble into elliptical disc-shaped particles

A. H. Larsen, N. T. Johansen, M. Gajhede, L. Arleth, S. R. Midtgaard

This study examines the structural formation of lipid-bound ApoE3 particles, revealing elliptical disc shapes and differences in morphology between full-length and truncated forms.

bioRxiv · Sep 30, 2020Biochemistry

Structure and dynamics of a nanodisc by integrating NMR, SAXS and SANS experiments with molecular dynamics simulations

T. Bengtsen, V. L. Holm, L. R. Kjolbye, S. R. Midtgaard, N. T. Johansen, G. Tesei, S. Bottaro, B. Schiott, L. Arleth, K. Lindorff-Larsen

This study integrates NMR, SAXS, SANS, and molecular dynamics simulations to characterize the structure and dynamics of two nanodiscs, revealing conformational heterogeneity and lipid ordering differences.

bioRxiv · Jun 23, 2020Biophysics