Cysteine Restriction-Specific Effects of Sulfur Amino Acid Restriction on Lipid Metabolism
S. N. Nichenametla, D. A. Mattocks, D. Cooke, V. Midya, V. L. Malloy, W. Mansilla, B. Ovrebo, C. Turner, N. E. Bastani, J. Sokolova, M. Pavlikova, J. P. Richie, A. K. Shoveller, H. Refsum, T. Olsen, , G. P. Ables
This study shows that cysteine restriction, not methionine restriction, drives anti-adiposity effects of sulfur amino acid restriction by increasing serinogenesis and altering metabolic pathways.
bioRxiv · May 14, 2022Biochemistry