Blocking IL-10 signaling with soluble IL-10 receptor restores specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum
G. G. Sa Oliveira, C. O. Santos, S. F. Costa, F. S. Souza, J. M. F. Mendes, C. G. M. Pinheiro, D. R. M. Moreira, L. K. Silva, V. M. F. Lima
This study identifies and characterizes a canine soluble IL-10 receptor that blocks IL-10 signaling and restores lymphoproliferative responses in dogs with Leishmania infantum infection.
bioRxiv · Sep 2, 2020Immunology