Induction of AMPK activation by N,N-Diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers
J. Johnson, P. Rychahou, V. M. Sviripa, H. L. Weiss, C. Liu, D. Watt, B. M. Evers
This paper tests the effects of FND-4b, a novel AMPK activator, on breast cancer cell proliferation and apoptosis, finding it reduces growth and increases apoptosis in both estrogen-receptor positive and triple-negative breast cancer cells.
bioRxiv · Dec 6, 2018Cancer Biology