H. L. Weiss

Integrin α6β4 signaling switches DNA repair from homologous recombination to non-homologous end-joining pathway to sensitize breast cancer cells to cisplatin

This study shows integrin α6β4 signaling shifts DNA repair from homologous recombination to non-homologous end joining in TNBC, increasing sensitivity to cisplatin.

Induction of AMPK activation by N,N-Diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

This paper tests the effects of FND-4b, a novel AMPK activator, on breast cancer cell proliferation and apoptosis, finding it reduces growth and increases apoptosis in both estrogen-receptor positive and triple-negative breast cancer cells.