The different effect of pharmacological or low-doses of IFN-γ in endothelial cells are mediated by different intracellular signaling pathways
A. Cazzaniga, V. Miranda, S. Castiglioni, J. A. M. Maier
This study shows that pharmacological and low-dose IFN-γ affect endothelial cells through distinct signaling pathways: JAK/STAT for growth inhibition and ERK for migration.
bioRxiv · Sep 13, 2022 · PreprintPharmacology & Toxicology