Emergence of a novel immune-evasion strategy from an ancestral protein fold in bacteriophage Mu
S. Karambelkar, S. Udupa, V. N. Gowthami, S. G. Ramachandra, G. Swapna, V. Nagaraja
This paper identifies acetyl CoA and iron as essential for the methylcarbamoylation of phage Mu DNA, revealing a novel mechanism involving Fe-S cluster-mediated free radical chemistry.
bioRxiv · Dec 2, 2019Biochemistry