Asynchrony between virus diversity and antibody selection limits influenza virus evolution
D. H. Morris, V. N. Petrova, F. W. Rossine, E. Parker, B. T. Grenfell, R. Neher, S. A. Levin, C. A. Russell
The paper shows that the timing mismatch between virus growth and antibody selection limits antigenic evolution within hosts, explaining global selectivity and local neutrality in influenza.
bioRxiv · Apr 27, 2020Evolutionary Biology