Author

C. A. Russell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Eggink· 2 shared M. D. de Jong· 2 shared R. M. Vigeveno· 2 shared A. Fox· 1 shared A. J. W. te Velthuis· 1 shared A. X. Han· 1 shared B. F. Koel· 1 shared B. T. Grenfell· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

D. Eggink

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Author profile →

4 papers

Recent·Most cited

A SARS-CoV-2 mini-genome assay based on negative-sense RNA to study replication inhibitors and emerging mutations

T. Vial, M. S. Oade, C. A. Russell, D. Eggink, A. J. W. te Velthuis

This paper develops a mini-genome assay using negative-sense RNA to study SARS-CoV-2 replication inhibitors and mutations, offering high sensitivity and ease of use in standard labs.

bioRxiv · Jun 28, 2021 · PreprintMicrobiology

Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

A. X. Han, Z. C. Felix Garza, M. R. A. Welkers, R. M. Vigeveno, N. D. Tran, T. Q. M. Le, Q. T. Pham, D. T. Dang, T. N. A. Tran, M. T. Ha, T. H. Nguyen, Q. T. Le, T. H. Le, T. B. N. Hoang, K. Chokephaibulkit, , C. A. Russell

This study examines within-host evolutionary dynamics of seasonal and pandemic influenza A viruses in young children, finding that nonsynonymous mutations decrease over time in A/H1N1pdm09 but increase in A/H3N2 due to mutation-selection balance.

bioRxiv · Mar 20, 2021Microbiology

Asynchrony between virus diversity and antibody selection limits influenza virus evolution

D. H. Morris, V. N. Petrova, F. W. Rossine, E. Parker, B. T. Grenfell, R. Neher, S. A. Levin, C. A. Russell

The paper shows that the timing mismatch between virus growth and antibody selection limits antigenic evolution within hosts, explaining global selectivity and local neutrality in influenza.

bioRxiv · Apr 27, 2020Evolutionary Biology

Disparate evolution of virus populations in upper and lower airways of mechanically ventilated patients

B. F. Koel, F. van Someren Greve, R. M. Vigeveno, M. Pater, C. A. Russell, M. D. de Jong

This study compares genetic variation of influenza virus in upper and lower respiratory tracts of ventilated patients, finding divergent evolutionary trajectories in different airway compartments.

bioRxiv · Jan 2, 2019 · PreprintMicrobiology