Maintaining oxidized H3 in heterochromatin is required for the oncogenic capacity of triple-negative breast cancer cells
G. Serra-Bardenys, T. V. Tian, E. Blanco, J. Querol, L. Pascual-Reguant, B. Morancho, M. Escorihuela, S. Segura-Bayona, G. Verde, R. Aiese Cigliano, A. Millanes-Romero, C. Jerónimo, P. Nuciforo, S. Simonetti, C. Viaplana, , S. Peiró
This study identifies the role of H3K4ox in maintaining heterochromatin structure in TNBC cells and shows its necessity for oncogenic properties.
bioRxiv · Jan 30, 2020 · PreprintCancer Biology