Author

T. V. Tian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. Arribas· 2 shared J. Querol· 2 shared L. Pascual-Reguant· 2 shared S. Peiro· 2 shared A. Ganez Zapater· 1 shared A. García de Herreros· 1 shared A. Klonizakis· 1 shared A. Leutz· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

J. Arribas

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Author profile →

3 papers

Recent·Most cited

Carm1 regulates the speed of C/EBPa-induced transdifferentiation by a cofactor stealing mechanism

G. T. Garcia, E. Kowenz-Leutz, T. V. Tian, A. Klonizakis, J. Lerner, L. De Andres-Aguayo, C. Berenguer, M. P. Carmona, M. V. Casadesus, R. Bulteau, M. Francesconi, S. Peiro, K. S. Zaret, A. Leutz, T. Graf

This study shows that a C/EBP mutation accelerates B cell to macrophage transdifferentiation by altering PU.1 interactions, and that Carm1 methylation regulates this process.

bioRxiv · Oct 3, 2022Cell Biology

The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer

L. Pascual-Reguant, T. V. Tian, D. Datta, D. Cianferoni, S. Kourtis, A. Ganez Zapater, C. Cannata, Q. Serra Camprubi, L. Espinar, M. Guirola, J. Querol, A. Miro Canturri, J. Arribas, L. Serrano, S. Peiro, S. Sdelci

This study shows that inhibiting LOXL2 and BRD4 together reduces triple-negative breast cancer proliferation by disrupting the BRD4S-LOXL2-MED1 interaction that controls cell cycle gene expression.

bioRxiv · May 27, 2022 · PreprintCancer Biology

Maintaining oxidized H3 in heterochromatin is required for the oncogenic capacity of triple-negative breast cancer cells

G. Serra-Bardenys, T. V. Tian, E. Blanco, J. Querol, L. Pascual-Reguant, B. Morancho, M. Escorihuela, S. Segura-Bayona, G. Verde, R. Aiese Cigliano, A. Millanes-Romero, C. Jerónimo, P. Nuciforo, S. Simonetti, C. Viaplana, , S. Peiró

This study identifies the role of H3K4ox in maintaining heterochromatin structure in TNBC cells and shows its necessity for oncogenic properties.

bioRxiv · Jan 30, 2020 · PreprintCancer Biology