Substrate identification and specificity profiling of deubiquitylases against endogenously-generatedubiquitin-protein conjugates
V. Rossio, J. A. Paulo, X. Liu, S. P. Gygi, R. W. King
The paper identifies high-impact DUBs and their substrates using Xenopus egg extract and proteomics, revealing substrate characteristics influencing DUB specificity.
bioRxiv · Dec 20, 2023 · PreprintBiochemistry