Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and -deficient cells
J. Michelena, S. Pellegrino, V. Spegg, M. Altmeyer
The paper shows that 53BP1 recruitment to damaged replicated chromatin is inefficient in both BRCA1-proficient and -deficient cells, revealing a dual switch model in DNA repair pathway choice.
bioRxiv · Feb 24, 2020Cell Biology