Human POT1 Unfolds G-Quadruplexes by Conformational Selection
J. B. Chaires, R. D. Gray, W. L. Dean, R. Monson, L. W. DeLeeuw, V. Stribinskis, J. O. Trent
This paper investigates how POT1 unfolds human telomeric G-quadruplexes through a conformational selection mechanism, supported by kinetic, thermodynamic, and computational data.
bioRxiv · Jul 2, 2019Biophysics