The kinase inhibitor Palbociclib is a potent and specific RNA-binding molecule
M. D. Shortridge, V. Vidalala, G. Varani
The paper identifies Palbociclib as an RNA-binding molecule with nM affinity for HIV-1 TAR RNA, demonstrating that RNA-targeting drugs can achieve potent and specific binding.
bioRxiv · Jan 20, 2022 · PreprintBiochemistry