Extratubular polymerized uromodulin induces leukocyte recruitment and inflammation in vivo
R. Immler, B. Lange-Sperandio, T. Steffen, H. Beck, J. Roth, G. Hupel, F. Pfister, B. Popper, B. Uhl, H. Mannell, C. A. Reichel, V. Vielhauer, J. Scherberich, M. Sperandio, M. Pruenster
This study shows extratubular polymerized uromodulin induces inflammation by recruiting leukocytes and affecting vascular permeability in vivo.
bioRxiv · Jul 18, 2020Immunology