Kinase-independent inhibition of cyclophosphamide-induced pathways protects the ovarian reserve and prolongs fertility
G. Bellusci, V. Iannizzotto, S. Ciccone, L. Mattiello, E. Maiani, V. Villani, M. Diederich, S. Gonfloni
The paper identifies cyclophosphamide-induced signaling pathways that deplete ovarian reserve and shows that kinase-independent inhibition can protect fertility.
bioRxiv · Jan 21, 2019Cell Biology