Distinct cancer-associated fibroblast states drive clinical outcomes in high-grade serous ovarian cancer and are regulated by TCF21
A. Hussain, V. Voisin, S. Poon, J. Dmytryshyn, C. Richman, J. Meens, V. W. Ho, K. H. Tang, J. Paterson, B. Clarke, M. Bernardini, G. Bader, B. Neel, L. Ailles
This study identifies two distinct cancer-associated fibroblast subtypes in high-grade serous ovarian cancer and shows their differential impact on patient outcomes and tumor progression.
bioRxiv · May 10, 2019Cancer Biology