Selective ablation of adult GFAP-expressing tanycytes leads to hypogonadotropic hypogonadism in males
Lucile Butruille, Martine Batailler, Marie-Line Cateau, Ariane Sharif, Valérie Leysen, Vincent Prévot, Pascal Vaudin, Delphine Pillon, Martine Migaud
This study shows that selective ablation of adult hypothalamic GFAP-expressing tanycytes causes hypogonadotropic hypogonadism in males by reducing GnRH neurons and testosterone levels.
bioRxiv · Jul 31, 2021 · PreprintNeuroscience