Clinical-grade Plant-made nanomaterials: from Process Design to the construction of a Manufacturing facility.
Denise Pivotto, Anthony Rosa, Aya Maged Elsheikh, Elisa Gecchele, Roberta Zampieri, Alessia Raneri, Valentina Garonzi, Linda Avesani
This study develops a GMP-compliant manufacturing process for TBSV-based nanoparticles designed to induce immune tolerance in autoimmune diseases and evaluates its scalability and environmental impact.
Frontiers in Plant Science · Jan 2, 2026Peer-reviewedBioengineering