Efficient generation of human dendritic cells from iPSC by introducing a feeder-free expansion step for hematopoietic progenitors
Zahra Elahi, Vanta J. Jameson, Magdaline Sakkas, Suzanne Butcher, Justine D. Mintern, Kristen J. Radford, Christine Anne Wells
This paper develops an in vitro protocol to generate human dendritic cells from iPSC with a feeder-free expansion step, resulting in DC1-like cells that show functional characteristics similar to monocyte-derived DCs.
Journal of Leukocyte Biology · Apr 12, 2025Peer-reviewedCell Biology