Vasiliki Kostiou

Different responses to cell crowding determine the clonal fitness of p53 and Notch inhibiting mutations in squamous epithelia

The paper shows that p53 and DN_Maml1 mutations have different clonal fitness responses to cell crowding in epithelial tissues, consistent with mutation distributions in human datasets.

Methods for analysing lineage tracing datasets

The paper compares methods for analysing lineage tracing datasets and recommends an approximate Bayesian computation approach for parameter estimation.