MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells
Yuichiro Saito, Venny Santosa, Kei-ichiro Ishiguro, Masato T. Kanemaki
This study identifies MCMBP as essential for MCM2-7 hexamer assembly in human cells, showing its role in DNA replication and its potential as a target for p53-deficient cancers.
eLife · Apr 11, 2022Peer-reviewedMolecular Biology