Modeling of human MLH1 and MLH3 variants in mice reveals novel functions of MutLγ in meiotic DNA repair and the ovarian reserve
Xinbao Ding, Vertika Singh, John C. Schimenti
This study models human MLH1 and MLH3 variants in mice, revealing MutLγ's roles in meiotic DNA repair and ovarian reserve maintenance through multiple mechanisms.
bioRxiv · Oct 27, 2026 · PreprintGenetics