Probing the dynamic structure-function and structure-free energy relationships of the corona virus main protease with Biodynamics theory
Hongbin Wan, Vibhas Aravamuthan, Robert A. Pearlstein
The paper applies Biodynamics theory to study the dynamic structural changes and energy relationships in SARS-CoV-2 Mpro during substrate-induced activation and inhibition.
ACS Pharmacology & Translational Science · Nov 6, 2020Peer-reviewedSystems Biology