Author

Hongbin Wan

Novartis (Switzerland)ORCID 0000-0002-4875-531XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

Robert A. PearlsteiniD· 2 shared Gianluca SelvaggioiD· 1 shared Vibhas Aravamuthan· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 2 mutual co-author links

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2 shared papersSystems Biology

Robert A. PearlsteinORCID

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2 papers

Recent·Most cited

Probing cellular arrhythmogenesis using the O'Hara-Rudy model of the undiseased human ventricular cardiomyocyte

Gianluca Selvaggio, Hongbin Wan, Robert A. Pearlstein

This paper uses the O'Hara-Rudy model to study how different perturbations affect ventricular action potential morphology and arrhythmogenesis in midmyocytes.

bioRxiv · Nov 15, 2020 · PreprintSystems Biology

Probing the dynamic structure-function and structure-free energy relationships of the corona virus main protease with Biodynamics theory

Hongbin Wan, Vibhas Aravamuthan, Robert A. Pearlstein

The paper applies Biodynamics theory to study the dynamic structural changes and energy relationships in SARS-CoV-2 Mpro during substrate-induced activation and inhibition.

ACS Pharmacology & Translational Science · Nov 6, 2020Peer-reviewedSystems Biology