The altered T cell landscape in Systemic Sclerosis patients is characterized by dysfunctional type 1 immunity.
Victoria Volfson-Sedletsky, Hannah A. DeBerg, Mitchell L. Fahning, Ian R. Rifkin, Andreea M. Bujor, Daniel Campbell, Peter A. Morawski, Anna C. Belkina, Hans Dooms
This study identifies dysfunctional type 1 immunity in SSc patients through altered T cell subsets and reduced IFN-γ production.
bioRxiv · Dec 13, 2025 · PreprintImmunology