Microinjection-based Single-Cell Toxicological Assessment Reveals How Physiological Levels of PFOS Impair Oocyte Maturation and Developmental Competence
MD HASANUR ALAM, Shuangqi Wang, Juan Dong, Vidhi Patel, Wenjie Yang, Leyi Wang, Huanyu Qiao
This paper uses a microinjection-based single-oocyte assay to show that PFOS impairs oocyte maturation and early development by causing spindle defects, oxidative stress, and transcriptional dysregulation.
bioRxiv · May 29, 2026 · PreprintCell Biology