Huanyu Qiao

The paper introduces digital-chromosome-banding to analyze meiotic silencing dynamics and identifies sexual dimorphism in meiotic silencing processes.

This paper uses a microinjection-based single-oocyte assay to show that PFOS impairs oocyte maturation and early development by causing spindle defects, oxidative stress, and transcriptional dysregulation.

This study shows that exposure to a phthalate metabolite mixture impairs mouse oocyte maturation and causes meiotic defects and DNA damage.

This study shows SUMO regulates meiotic chromosome length and crossover rate in mice by affecting chromatin loop and axis organization.

This study isolates meiotic spindles from mouse oocytes to investigate migration forces during asymmetric division, finding a net tensile force of ~680 pN.

The paper identifies PTBP1's role in regulating alternative splicing of actin regulators to control Sertoli cell actin cytoskeleton dynamics during spermatogenesis.

This study identifies Dzip1 as a novel germ plasm component in Xenopus and zebrafish that interacts with Dazl to regulate primordial germ cell development.

This study measures chromosome stiffness in mouse oocytes across cell cycle stages and age, finding increased stiffness in metaphase I oocytes and age-related stiffness changes.

The paper investigates the role of RNA polymerase II pausing in spermatogenesis, showing it is essential for gene expression and meiosis completion.

This study shows RNF212 mediates oocyte quality control by impeding DNA break repair during meiosis, ensuring defective eggs are eliminated.

The paper shows that SUMO and ubiquitin-proteasome systems regulate meiotic prophase events in mouse by controlling protein turnover through RNF212 and HEI10.