Serotonin2A receptors in the medial prefrontal cortex do not drive DOI-induced head-twitch responses in rodents
Ratna Mahathi Vuruputuri, Vaishnavi Reghunath, Shreyasi Mukherjee, Gopesh K. Bajre, Pratik Rajeev Chaudhari, Vir Gahrotra, Vidita A. Vaidya
This study investigates the role of 5-HT2A receptors in the medial prefrontal cortex in DOI-induced head-twitch responses in rodents, finding no contribution from mPFC 5-HT2ARs.
bioRxiv · Oct 11, 2026 · PreprintNeuroscience