Two transmembrane transcriptional regulators coordinate to activate chitin-induced natural transformation in Vibrio cholerae
Allison C. Hullinger, Virginia E. Green, Catherine A. Klancher, Triana N. Dalia, Ankur B. Dalia
This paper shows that ChiS and TfoS, two transmembrane transcriptional regulators in V. cholerae, work together to activate natural transformation in response to chitin by recruiting the PtfoR promoter to the membrane and facilitating TfoS interaction.
PLoS Genetics · Feb 18, 2025Peer-reviewedMicrobiology