A molecular clock controls periodically driven cell migration in confined spaces
Sung Hoon Lee, Jay Hou, Archer Hamidzadeh, Muhammad Sulaiman Yousafzai, Visar Ajeti, Hao Chang, David J. Odde, Michael P. Murrell, Andre Levchenko
The paper identifies a molecular clock mechanism that regulates cell migration in confined spaces through cyclic RhoA activity driven by Ca2+ and GEF-H1 oscillations.
Cell Systems · Jun 8, 2022Peer-reviewedSystems Biology